Insulin action on skeletal muscle protein metabolism during catabolic states

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Insulin action on skeletal muscle protein metabolism during catabolic states.

Insulin plays a major role in the regulation of skeletal muscle protein turnover but its mechanism of action is not fully understood, especially in vivo during catabolic states. These aspects are presently reviewed. Insulin inhibits the ATP-ubiquitin proteasome proteolytic pathway which is presumably the predominant pathway involved in the breakdown of muscle protein. Evidence of the ability of...

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ژورنال

عنوان ژورنال: Reproduction Nutrition Development

سال: 1999

ISSN: 0926-5287

DOI: 10.1051/rnd:19990104